The Pacific Center for Molecular Biodiversity (PCMB) is the primary cryopreservation facility for Pacific-wide biodiversity. The PCMB collection includes more than 40,000 tissue and genetic samples from marine, terrestrial, and freshwater plants and animals throughout the tropical Pacific, many of which represent threatened, endangered, or extinct species. The center promotes and facilitates biodiversity research and conservation using modern genomic approaches to expand the knowledge and understanding of the natural and cultural history of Hawai‘i and the Pacific region broadly. The laboratory is an integral component of the Museum’s knowledge core and aims to enhance scientific and public understanding of biodiversity research, and foster stewardship and conservation of Hawaiian biological and cultural heritage.